Effects of a randomized controlled trial of a brief, student-nurse led, parent-based sexual health intervention on parental protective factors and HPV vaccination uptake

Abstract Background Parents play a pivotal role in adolescent sexual health and Human Papillomavirus (HPV) vaccination. Nurses are on the frontlines of healthcare critical promoting HPV vaccination parent-child communication. We enhanced Families Talking Together (FTT) parent-based curriculum to include vaccinations herein, FTT + HPV, trained student nurses provide strong communication endorsement. Methods Using randomized attention-controlled trial design, we examined efficacy among 519 parents their 11–14 year old youth recruited from medically underserved communities between 2015 2018. Participants were 22 after-school programs (e.g., Boys Girls Clubs) 19 charter schools. For parents, protective factors including parental involvement. youth, knowledge, communication, connectedness. To assess initiation completion, searched IMMTRAC immunization registry records for 85% used report without records. Group differences calculated using estimated mean difference at one- six months post-intervention with significance set p < 0.05 level. Results Baseline rates low 55.7%. No significant groups was seen or completion by one-month post-intervention. However, six-months post intervention, there 70.3% intervention group initiating series vs. 60.6% control ( = 0.02). found six-months. There condom knowledge 0.04), connectedness frequency 0.001) greater improvement group. Rates activity remained both throughout six-month follow-up period. Conclusion A brief delivered can improve outcomes factors, rates. Trial registration ClinicalTrials.gov Identifier: NCT02600884 . Prospectively r egistered September 1, 2015.